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2,* Start FARXIGA today in your patients with HFrEF and an eGFR. 1% A1C Both Jardiance (Empagliflozin) and Farxiga (Dapagliflozin) have been found to be superior to placebo in patients with heart failure and reduced ejection fraction (HFrEF) regardless of whether they have diabetes or not. Pfizer intends to submit for regulatory approval in fall 2022 NEW YORK-(BUSINESS WIRE)- Pfizer Inc. Please see Prescribing Information and Medication Guide for FARXIGA FARXIGA is a once-daily pill proven to help lower A1C, along with diet and exercise. FARXIGA helps save lives in patients by reducing the risk of CV death and hospitalization for heart failure. Metformin XR alone lowered A1C by 1. Emily (36) & DH Kevin (37), married 10/24/10 9/22/12 ECTOPIC pregnancy. In a pool of 12 placebo-controlled studies, the most common adverse reactions (≥5%) associated with FARXIGA 5 mg, 10 mg, and placebo respectively were female genital mycotic infections (8. For all other indications, the recommended dose is 10 mg orally once daily Farxiga is an oral medication that is used alongside diet and exercise to lower blood glucose levels in people with type 2 diabetes, often in addition to other medications. FARXIGA + METFORMIN XR helps lower A1C by this number of points when used as the first drug therapy for type 2 diabetes. FARXIGA is not expected to be effective in these populations. The new drug won't help PCOS or hormone balance but it would be an additional tool to keep your blood sugar low if your current treatments aren't enough. Dose can be increased to 10 mg orally once daily for additional glycemic control. FARXIGA is not expected to work if you have these conditions. The DECLARE-TIMI demonstrated a 27% reduction in heart failure in the Farxiga (Dapagliflozin) group compared to placebo Farxiga causes excess glucose to be excreted in the urine (instead of hanging around in your blood causing problems). 1 FARXIGA is a first-line GDMT with Class 1A recommendation for HFrEF in the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure. 2%), and urinary tract infections (5. DOSING To improve glycemic control, the recommended starting dose is 5 mg orally once daily. COVID-19 vaccine and COMIRNATY (COVID-19 Vaccine, mRNA) (BNT162b2) (including potential in children 6. * *Average reduction with 5mg + metformin XR when starting at 9.

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